Hiromi Kojima Selected Research

Cholesteatoma

11/2022	Retrograde mastoidectomy with canal wall reconstruction versus intact canal wall tympanomastoidectomy for cholesteatoma with minimal mastoid extension.
4/2021	Transcanal endoscopic approach for pars flaccida cholesteatoma using a 70-degree angled endoscope.
1/2021	Menin-MLL inhibitor blocks progression of middle ear cholesteatoma in vivo.
1/2021	Super-enhancer Acquisition Drives FOXC2 Expression in Middle Ear Cholesteatoma.
12/2020	The impact of middle ear aeration on surgical outcome after intact canal wall tympanoplasty for cholesteatoma.
1/2020	L1CAM-ILK-YAP Mechanotransduction Drives Proliferative Activity of Epithelial Cells in Middle Ear Cholesteatoma.
1/2013	Cholesteatoma fibroblasts promote epithelial cell proliferation through overexpression of epiregulin.
12/2008	Endoscope-assisted surgery via the middle cranial fossa approach for a petrous cholesteatoma.
9/2003	[Congenital middle ear cholesteatoma: experience in 48 cases].

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Hiromi Kojima Research Topics

Disease

9	Cholesteatoma 11/2022 - 09/2003
9	Neoplasms (Cancer) 06/2022 - 06/2002
7	Otitis Media 03/2022 - 08/2010
5	Middle Ear Cholesteatoma 12/2022 - 01/2013
5	Squamous Cell Carcinoma (Epidermoid Carcinoma) 06/2022 - 06/2002
5	Hearing Loss (Hearing Impairment) 06/2018 - 06/2010
3	Hemorrhage 01/2021 - 06/2016
3	Seasonal Allergic Rhinitis (Hay Fever) 01/2021 - 01/2019
3	Nasal Polyps (Nasal Polyp) 01/2020 - 09/2018
3	Squamous Cell Carcinoma of Head and Neck 01/2017 - 06/2002
3	Fabry Disease (Fabry's Disease) 01/2013 - 12/2009
2	Neoplasm Metastasis (Metastasis) 06/2022 - 01/2017
2	Infections 01/2022 - 08/2010
2	Hyperplasia 03/2021 - 02/2015
2	Leukemia 01/2021 - 01/2005
2	Hypersensitivity (Allergy) 01/2021 - 01/2019
2	Congenital Cholesteatoma 04/2020 - 09/2003
2	Rhinosinusitis 01/2020 - 09/2018
1	Apnea 12/2022
1	Otitis Externa 06/2022
1	Pathologic Constriction (Stenosis) 04/2022
1	Maxillary Sinus Neoplasms 08/2021
1	Nasal Obstruction 06/2021
1	Sinusitis 03/2021
1	Obstructive Sleep Apnea 12/2020
1	IGA Glomerulonephritis (IGA Nephropathy) 01/2020
1	Mumps 06/2018
1	Eosinophilia 01/2018
1	Fibrosis (Cirrhosis) 01/2018
1	Oropharyngeal Neoplasms 01/2017
1	Papillomavirus Infections 01/2017
1	Lymphatic Metastasis 01/2017
1	Vertigo (Positional Vertigo) 09/2016
1	Sensorineural Hearing Loss 09/2016
1	Epistaxis (Nosebleed) 06/2016
1	Deafness (Deaf Mutism) 05/2015
1	Otosclerosis 01/2014

Drug/Important Bio-Agent (IBA)

4	Proteins (Proteins, Gene)FDA Link 06/2022 - 03/2015
3	AllergensIBA 01/2021 - 01/2019
2	Cisplatin (Platino)FDA LinkGeneric 08/2021 - 06/2006
2	Fibroblast Growth Factor 7 FDA Link 01/2021 - 01/2018
2	Lysine (L-Lysine)FDA Link 01/2021 - 01/2021
2	Histones (Histone)IBA 01/2021 - 01/2021
2	CytokinesIBA 06/2019 - 09/2015
2	Messenger RNA (mRNA)IBA 09/2018 - 01/2013
2	SteroidsIBA 06/2018 - 09/2016
2	DNA (Deoxyribonucleic Acid)IBA 01/2017 - 05/2015
2	EnzymesIBA 12/2009 - 06/2002
1	Oxygen (Dioxygen)IBA 12/2022
1	MicroRNAs (MicroRNA)IBA 06/2022
1	ErbB Receptors (EGF Receptor)IBA 06/2022
1	Epidermal Growth Factor (EGF)IBA 06/2022
1	Phosphatidylinositols (Phosphatidylinositol)IBA 06/2022
1	Coloring Agents (Dyes)IBA 08/2021
1	salicylhydroxamic acid (SHAM)IBA 03/2021
1	histone H3 trimethyl Lys4IBA 01/2021
1	ChromatinIBA 01/2021
1	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 01/2021
1	ParaffinIBA 01/2021
1	Vasoconstrictor AgentsIBA 01/2020
1	galactosyl-deficient IgA1IBA 01/2020
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2020
1	Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA 01/2020
1	AntibodiesIBA 01/2020
1	ChemokinesIBA 06/2019
1	AntigensIBA 01/2019
1	Immunoglobulin E (IgE)IBA 01/2019
1	decysinIBA 09/2018
1	Mumps Vaccine (Vaccine, Mumps)IBA 06/2018
1	VaccinesIBA 06/2018
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2018
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2018
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2018
1	Interleukin-4 (Interleukin 4)IBA 01/2018
1	Cyclin D1IBA 01/2018
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2018
1	Interleukin-5 (Interleukin 5)IBA 01/2018
1	Eosinophil-Derived NeurotoxinIBA 09/2015
1	Pancreatic Elastase (Elastase)IBA 09/2015

Therapy/Procedure

7	Therapeutics 03/2022 - 06/2006
5	Transplantation 03/2022 - 02/2015
4	Tympanoplasty 04/2022 - 12/2020
4	Operative Surgical Procedures 03/2021 - 09/2003
3	Mastoidectomy 12/2022 - 04/2020
3	Endoscopes 04/2021 - 12/2008
2	Radiotherapy 08/2021 - 08/2010
2	Sutures (Suture) 01/2021 - 03/2016
1	Cell Transplantation 12/2021
1	Suture Techniques 06/2021
1	Oral Administration 01/2021
1	Conservative Treatment 01/2021
1	Continuous Positive Airway Pressure 12/2020
1	Kidney Transplantation 01/2020
1	Immunotherapy 01/2019
1	Parenteral Nutrition 06/2018
1	Cautery 06/2016
1	Surgical Instruments (Clip) 06/2016
1	Electrocoagulation (Electrocautery) 06/2016
1	Stapes Surgery (Stapedectomy) 01/2014
1	Enzyme Replacement Therapy 01/2013